Joint Research Group Macromolecular Crystallography
The HZB-MX BioLab: A Dedicated Facility for Protein Research & Sample Preparation
The HZB-MX BioLab is a fully equipped S1 facility available to the entire HZB user platform. It provides the necessary equipment and expertise for protein production, purification and characterization supporting research in structural biology and biochemistry. The BioLab is an essential service unit for biological and biochemical experiments, particularly for sample preparation in X-ray diffraction studies.
Our Facilities
Located just a 6-minute walk from the BESSY II experimental hall at Volmerstr. 7a, the BioLab consists of four S1 laboratory rooms along with office space and a shared kitchen/break room. Each lab is tailored for specific functions:
- Protein Purification Lab:
- Enables the preparation of target proteins from prokaryotic and eukaryotic cell cultures or native protein sources.
- Cell Culture Lab:
- Supports procaryotic and eukaryotic protein expression featuring equipment such as ÄKTA Pure chromatography systems and Tritec climatic cabinets.
- Protein Characterization Labs:
- Equipped for biochemical and biophysical characterization, buffer optimization, and stability testing.
Future Developments
The HZB-MX Biolab is continuously evolving to meet the needs of our users:
- A 4°C cold lab for protein purification and storage
- Additional space for crystallization incubators
- A bioreactor for larger-scale protein production
- An LC/MS system for precise protein characterization
The HZB-MX BioLab is open to internal and external users, providing a practical and well-equipped environment for biological sample preparation. If you need support for protein research, crystallization, or biochemical studies, our facilities are here to assist you.
👉 Contact us to learn more or to book lab time.