Joint Research Group Macromolecular Crystallography
Seventh Joint Berlin MX-day
Axon 1 - MDC.C
Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft
Campus Buch, Robert-Rössle-Str. 10, 13125 Berlin
28 September 2016
Meeting Agenda
08:30 - 09:00 | Coffee and Croissants |
09:00 - 09:15 | Udo Heinemann Greetings |
Session I – Protein-RNA Interaction (Chair: Oliver Daumke, MDC) | |
09:15 ‐ 09:45 | Sutapa Chakrabarty (FU) Molecular mechanisms of targeted mRNA degradation |
09:45 ‐ 10:05 | Nelly Said (FU) Structural basis for hijacking the E. coli transcriptional machinery by protein N of phage λ |
10:05 ‐ 10:25 | Jia Junqiao (FU) Structure and function of the spliceosomal protein, Snu114 |
10:25 ‐ 10:45 |
Ankur Garg (MDC) Regulation of innate immune responses by ribonuclease MCPIP3 |
10:45 - 10:55 |
Group Foto |
10:55 ‐ 11:20 | Coffee Break |
Session II – Viral Affairs (Chair: Markus Wahl, FU) | |
11:20 ‐ 11:50 | Ursula Neu (MPI Potsdam) A structural view on virus infection and antibody neutralization |
11:50 ‐ 12:10 | Daniel Olal (MDC) Structural insight into nucleocapsid assembly of Hantaviruses |
12:10 ‐ 12:40 | David Schwefel (Charité) Specificity modulation of cullin4-RING E3 ubiquitin ligases by retroviral accessory proteins |
12:40 ‐ 13:50 | Lunch Break (MDC Mensa) |
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Session III – Membranes and Methods (Chair: Manfred Weiss, HZB) |
13:50 ‐ 14:10 | Manuel Hessenberger (MDC) Mic60-mediated membrane remodeling controls formation of mitochondrial crista junction |
14:10 ‐ 14:30 |
Dennis Kwiatkowski (Charité) Specificity of the rhodopsin G-protein binding interface |
14:30 ‐ 14:50 |
Luisa Sauthof (Charité) |
14:50 ‐ 15:10 |
Martin Gerlach (HZB) The new HZB-MX beamline BL14.2 |
15:10 - 15:30 |
Karine Röwer (HZB) The expert data processing system XDSAPP |
15:30 ‐ 16:00 | Coffee Break |
Session IV – Ligand Finding, Binding and Specificity (Chair: Holger Dobbek, HU) | |
16:00 ‐ 16:30 |
Marc Nazaré (FMP) Case studies in medicinal chemistry – How to enhance the activity of initial screening hits |
16:30 ‐ 16:50 |
Anja Schütz (MDC) Targeting human tryptophan hydroxylase – A structure-guided drug design approach |
16:50 ‐ 17:10 |
Franziska Huschmann (HZB) Crystallographic fragment screening at the HZB |
17:10 ‐ 17:30 | Clarissa Eibl (FMP) Mechanism of partial agonism in AMPA-type glutamate receptors |
17:30 - 17:50 |
Martin Bommer (HU) A pocket that binds everything? The terminal enzyme in an oxygen-free respiratory chain |
18:00 ‐ end | BBQ |