Ochmann, M.; Vaz da Cruz, V.; Eckert, S.; Huse, N.; Föhlisch, A.: R-Group stabilization in methylated formamides observed by resonant inelastic X-ray scattering. Chemical Communications 58 (2022), p. 8834–8837
10.1039/d2cc00053a
Open Access Version
Abstract:
The inherent stability of methylated formamides is traced to a stabilization of the deep-lying σ-framework by resonant inelastic X-ray scattering at the nitrogen K-edge. Charge transfer from the amide nitrogen to the methyl groups underlie this stabilization mechanism that leaves the aldehyde group essentially unaltered and explains the stability of secondary and tertiary amides.