MX 14.3
MX_BEAMLINE_14.3
Publikationen
2024Marino, S.F.; Daumke, O.: Structure-based humanization of a therapeutic antibody for multiple myeloma. , Journal of Molecular Medicine 102 (2024), p. 1151-1161
doi: 10.1007/s00109-024-02470-4
2023
Wator, E.; Wilk, P.; Biela, A.; Rawski, M.; Zak, K.M.; Steinchen, W.; Bange, G.; Glatt, S.; Grudnik, P.: Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders. , Nature Communications 14 (2023), p. 1698/1-14
doi: 10.1038/s41467-023-37305-2
Maliuta, M.; Senkovska, I.; Thuemmler, R.; Ehrling, S.; Becker, S.; Romaka, V.; Bon, V.; Evans, J.D.; Kaskel, S.: Particle size-dependent flexibility in DUT-8(Cu) pillared layer metal-organic framework. , Dalton Transactions 52 (2023), p. 2816-2824
doi: 10.1039/d3dt00085k
Schmidt, A.; Kalms, J.; Lorent, C.; Katz, S.; Frielingsdorf, S.; Evans, R.M.; Fritsch, J.; Siebert, E.; Teutloff, C.; Armstrong, F.A.; Zebger, I.; Lenz, O.; Scheerer, P.: Stepwise conversion of the Cys6[4Fe-3S] to a Cys4[4Fe-4S] cluster and its impact on the oxygen tolerance of [NiFe]-hydrogenase. , Chemical Science 14 (2023), p. 11105-11120
doi: 10.1039/d3sc03739h
2022
Malecki, P.H.; Imiolczyk, B.; Barciszewski, J.; Czyrko-Horczak, J.; Sliwiak, J.; Gawel, M.; Wozniak, K.; Jaskolski, M.; Brzezinski, K.: Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803. , Acta Crystallographica Section D - Structural biology 78 (2022), p. 865-882
doi: 10.1107/S2059798322005605
Data-doi: 10.18150/JWPKAB
Data-doi: 10.18150/1KE3PW
Data-doi: 10.18150/IRFZHN
Krause, S.; Evans, J.D.; Bon, V.; Crespi, S.; Danowski, W.; Browne, W.R.; Ehrling, S.; Walenszus, F.; Wallacher, D.; Grimm, N.; Többens, D.M.; Weiss, M.S.; Kaskel, S.; Feringa, B.L.: Cooperative light-induced breathing of soft porous crystals via azobenzene buckling. , Nature Communications 13 (2022), p. 1951/1-10
doi: 10.1038/s41467-022-29149-z
von Horsten, S.; Lippert, M.L.; Geisselbrecht, Y.; Schuhle, K.; Schall, I.; Essen, L.O.; Heider, J.: Inactive pseudoenzyme subunits in heterotetrameric BbsCD, a novel short-chain alcohol dehydrogenase involved in anaerobic toluene degradation. , FEBS Journal 289 (2022), p. 1023-1042
doi: 10.1111/febs.16216
Bock-Bierbaum, T.; Funck, K.; Wollweber, F.; Lisicki, E.; von der Malsburg, K.; von der Malsburg, A.; Laborenz, J.; Noel, J.K.; Hessenberger, M.; Jungbluth, S.; Bernert, C.; Kunz, S.; Riedel, D.; Lilie, H.; Jakobs, S.; van der Laan, M.; Daumke, O.: Structural insights into crista junction formation by the Mic60-Mic19 complex. , Science Advances 8 (2022), p. eabo4946/1-12
doi: 10.1126/sciadv.abo4946
Kiliszek, A.; Pluta, M.; Bejger, M.; Rypniewski, W.: Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. , RNA 29 (2022), p. 44-54
doi: 10.1261/rna.079414.122
2021
Ehrling, S.; Reynolds, E.M.; Bon, V.; Senkovska, I.; Gorelik, T.E.; Evans, J.D.; Rauche, M.; Mendt, M.; Weiss, M.S.; Pöppl, A.; Brunner, E.; Kaiser, U.; Goodwin, A.L.; Kaskel, S.: Adaptive response of a metal-organic framework through reversible disorder-disorder transitions. , Nature Chemistry 13 (2021), p. 568-574
doi: 10.1038/s41557-021-00684-4
Hao, Y.; Wang, Y.; Dubrovin, V.; Avdoshenko, S.M.; Popov, A.A.; Liu, F.: Caught in Phase Transition: Snapshot of the Metallofullerene Sc3N@C70 Rotation in the Crystal. , Journal of the American Chemical Society 143 (2021), p. 612-616
doi: 10.1021/jacs.0c10758
Roztocki, K.; Rauche, M.; Bon, V.; Kaskel, S.; Brunner, E.; Matoga, D.: Combining In Situ Techniques (XRD, IR, and C-13 NMR) and Gas Adsorption Measurements Reveals CO2-Induced Structural Transitions and High CO2/CH4 Selectivity for a Flexible Metal-Organic Framework JUK-8. , ACS Applied Materials & Interfaces 13 (2021), p. 28503-28513
doi: 10.1021/acsami.1c07268
Krupp, Paul Ferdinand: Cryo-EM analysis of three macromolecular machines : RNA polymerase, ribosome, and E3 ubiquitin ligase. , Berlin, Freie Universität Berlin, Diss., 2021
Takenaka, M.; Takenaka, S.; Barthel, T.; Frink, B.; Haag, S.; Verbitskiy, D.; Oldenkott, B.; Schallenberg-Rüdinger, M.; Feiler, C.G.; Weiss, M.S.; Palm, G.J.; Weber, G.: DYW domain structures imply an unusual regulation principle in plant organellar RNA editing catalysis. , Nature Catalysis 4 (2021), p. 510-522
doi: 10.1038/s41929-021-00633-x
Wang, Y.; Velkos, G.; Israel, N.J.; Rosenkranz, M.; Büchner, B.; Liu, F.; Popov, A.A.: Electrophilic Trifluoromethylation of Dimetallofullerene Anions en Route to Air-Stable Single-Molecule Magnets with High Blocking Temperature of Magnetization. , Journal of the American Chemical Society 143 (2021), p. 18139-18149
doi: 10.1021/jacs.1c07021
Oebbeke, Matthias: Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A. , Uni Marburg, 2021
Fujdiarová, E.; Houser, J.; Dobes, P.; Paulíková, G.; Kondakov, N.; Kononov, L.; Hyrsl, P.; Wimmerová, M.: Heptabladed beta-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O methylated sugars and influence the host immune system. , FEBS Journal 288 (2021), p. 1343-1365
doi: 10.1111/febs.15457
Walenszus, F.; Evans, J.D.; Bon, V.; Schwotzer, F.; Senkovska, I.; Kaskel, S.: Integration of Fluorescent Functionality into Pressure-Amplifying Metal-Organic Frameworks. , Chemistry of Materials 33 (2021), p. 7964-7971
doi: 10.1021/acs.chemmater.1c01804
Pfahler, Julian: Strukturelle und funktionelle Untersuchungen der humanen Proteine DBC1, PARP1 und Sirt1 sowie ihrer Interaktionen. , Universität Bayreuth, 2021
2020
Niu, W.; Ma, J.; Soltani, P.; Zheng, W.; Liu, F.; Popov, A.A.; Weigand, J.J.; Komber, H.; Poliani, E.; Casiraghi, C.; Droste, J.; Hansen, M.R.; Osella, S.; Beljonne, D.; Bonn, M.; Wang, H.I.; Feng, X.; Liu, J.; Mai, Y.: A Curved Graphene Nanoribbon with Multi-Edge Structure and High Intrinsic Charge Carrier Mobility. , Journal of the American Chemical Society 142 (2020), p. 18293-18298
doi: 10.1021/jacs.0c07013
Pintar, S.; Borisek, J.; Usenik, A.; Perdih, A.; Turk, D.: Domain sliding of two Staphylococcus aureus N-acetylglucosaminidases enables their substrate-binding prior to its catalysis. , Communications Biology 3 (2020), p. 178/1-9
doi: 10.1038/s42003-020-0911-7
Ma, J.; Fu, Y.; Dmitrieva, E.; Liu, F.; Komber, H.; Hennersdorf, F.; Popov, A.A.; Weigand, J.J.; Liu, J.; Feng, X.: Helical Nanographenes Containing an Azulene Unit: Synthesis, Crystal Structures, and Properties. , Angewandte Chemie - International Edition 59 (2020), p. 5637-5642
doi: 10.1002/anie.201914716
Triandafillidis, D.P.; Parthenios, N.; Spiliopoulou, M.; Valmas, A.; Kosinas, C.; Gozzo, F.; Reinle-Schmitt, M.; Beckers, D.; Degen, T.; Pop, M.; Fitch, A.N.; Wollenhaupt, J.; Weiss, M.S.; Karavassili, F.; Margiolaki, I.: Insulin polymorphism induced by two polyphenols: New crystal forms and advances in macromolecular powder diffraction. , Acta Crystallographica Section D - Structural biology 76 (2020), p. 1065-1079
doi: 10.1107/s205979832001195X
Barkovskiy, Mikhail: Protein design of hapten-specific Anticalins as therapeutic antidotes and biochemical reagents. , München, Technische Universität München, Diss., 2020
Garai, B.; Bon, V.; Efimova, A.; Gerlach, M.; Senkovska, I.; Kaskel, S.: Reversible switching between positive and negative thermal expansion in a metal-organic framework DUT-49. , Journal of Materials Chemistry A 8 (2020), p. 20420-20428
doi: 10.1039/d0ta06830f
Röhm, S.; Schröder, M.; Dwyer, J.E.; Widdowson, C.S.; Chaikuad, A.; Berger, B.T.; Joerger, A.C.; Krämer, A.; Harbig, J.; Dauch, D.; Kudolo, M.; Laufer, S.; Bagley, M.C.; Knapp, S.: Selective targeting of the alpha C and DFG-out pocket in p38 MAPK. , European Journal of Medicinal Chemistry 208 (2020), p. 112721/1-35
doi: 10.1016/j.ejmech.2020.112721
Hansmann, P.; Brückner, A.; Kiontke, S.; Berkenfeld, B.; Seebohm, G.; Brouillard, P.; Vikkula, M.; Jansen, F.E.; Nellist, M.; Oeckinghaus, A.; Kümmel, D.: Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations. , Structure 28 (2020), p. 933–942
doi: 10.1016/j.str.2020.05.008
Nekvinda, J.; Rócycka, D.; Rykowski, S.; Wyszko, E.; Fedoruk-Wyszomirska, A.; Gurda, D.; Orlicka-Plocka, M.; Giel-Pietraszuk, M.; Kiliszek, A.; Rypniewski, W.; Bachorz, R.; Wojcieszak, J.; Grüner, B.; Olejniczak, A.: Synthesis of naphthalimide-carborane and metallacarborane conjugates: Anticancer activity, DNA binding ability. , Bioorganic Chemistry 94 (2020), p. 103432/1-16
doi: 10.1016/j.bioorg.2019.103432
Abylgazina, L.; Senkovska, I.; Ehrling, S.; Bon, V.; Petkov, P. St.; Evans, J.D.; Krylova, S.; Krylov, A.; Kaskel, S.: Tailoring adsorption induced switchability of a pillared layer MOF by crystal size engineering. , CrystEngComm 23 (2020), p. 538-549
doi: 10.1039/d0ce01497d
Ajayakumar, M.R.; Fu, Y.; Liu, F.; Komber, H.; Tkachova, V.; Xu, C.; Zhou, S.; Popov, A.A.; Liu, J.; Feng, X.: Tailoring Magnetic Features in Zigzag-Edged Nanographenes by Controlled Diels-Alder Reactions. , Chemistry - A European Journal 26 (2020), p. 7497-7503
doi: 10.1002/chem.202001130
Peter, M.F.; Gebhardt, C.; Glaenzer, J.; Schneberger, N.; de Boer, M.; Thomas, G.H.; Cordes, T.; Hagelueken, G.: Triggering Closure of a Sialic Acid TRAP Transporter Substrate Binding Protein through Binding of Natural or Artificial Substrates. , Journal of Molecular Biology : jmb 433 (2020), p. 166756/1-15
doi: 10.1016/j.jmb.2020.166756
Garai, B.; Bon, V.; Krause, S.; Schwotzer, F.; Gerlach, M.; Senkovska, I.; Kaskel, S.: Tunable Flexibility and Porosity of the Metal-Organic Framework DUT-49 through Postsynthetic Metal Exchange. , Chemistry of Materials 32 (2020), p. 889-896
doi: 10.1021/acs.chemmater.9b04769
2019
Liu, F.; Velkos, G.; Krylov, D.S.; Spree, L.; Zalibera, M.; Ray, R.; Samoylova, N.A.; Chen, C.-H.; Rosenkranz, M.; Schiemenz, S.; Ziegs, F.; Nenkov, K.; Kostanyan, A.; Greber, T.; Wolter, A.U.B.; Richter, M.; Buechner, B.; Avdoshenko, S.M.; Popov, A.A.: Air-stable redox-active nanomagnets with lanthanide spins radical-bridged by a metal-metal bond. , Nature Communications 10 (2019), p. 571/1-11
doi: 10.1038/s41467-019-08513-6
Feiler, C.G.; Wallacher, D.; Weiss, M.S.: An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering. , Journal of visualized experiments : JoVE 149 (2019), p. e59722/1-10 + video
doi: 10.3791/59722
Müller, J.; Kirschner, R.; Geyer, A.; Klebe, G.: Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage. , ACS Omega 4 (2019), p. 775–784
doi: 10.1021/acsomega.8b02364
Ehrling, S.; Senkovska, I.; Bon, V.; Evans, J.D.; Petkov, P.; Krupskaya, Y.; Kataev, V.; Wulf, T.; Krylov, A.; Vtyurin, A.; Krylova, S.; Adichtchev, S.; Slyusareva, E.; Weiss, M.S.; Buechner, B.; Heine, T.; Kaskel, S.: Crystal size versus paddle wheel deformability: selective gated adsorption transitions of the switchable metal-organic frameworks DUT-8(Co) and DUT-8(Ni). , Journal of Materials Chemistry A 7 (2019), p. 21459-21475
doi: 10.1039/c9ta06781g
Fudim, R.; Szczepek, M.; Vierock, J.; Vogt, A.; Schmidt, A.; Kleinau, G.; Fischer, P.; Bartl, F.; Scheerer, P.; Hegemann, P.: Design of a light-gated proton channel based on the crystal structure of Coccomyxa rhodopsin. , Science Signaling 12 (2019), p. eaav4203/1-12
doi: 10.1126/scisignal.aav4203
Gerth, F.; Jäpel, M.; Sticht, J.; Kuropka, B.; Schmitt, X.J.; Driller, J.H.; Loll, B.; Wahl, M.C.; Pagel, K.; Haucke, V.; Freund, C.: Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain. , Structure 27 (2019), p. 977-987.e5
doi: 10.1016/j.str.2019.03.020
Paulíková, G.; Houser, J.; Kašáková, M.; Oroszová, B.; Bertolotti, B.; Parkan, K.; Moravcová, J.; Wimmerová, M.: Fucosylated inhibitors of recently identified bangle lectin from Photorhabdus asymbiotica. , Scientific Reports 9 (2019), p. 14904/1-12
doi: 10.1038/s41598-019-51357-9
De Bortoli, F.; Neumann, A.; Kotte, A.; Timmermann, B.; Schueler, T.; Wahl, M.C.; Loll, B.; Heyd, F.: Increased versatility despite reduced molecular complexity: evolution, structure and function of metazoan splicing factor PRPF39. , Nucleic Acids Research 47 (2019), p. 5867–5879
doi: 10.1093/nar/gkz243
Rademacher, N.; Kuropka, B.; Kunde, S.-A.; Wahl, M.C.; Freund, C.; Shoichet, S.A.: Intramolecular domain dynamics regulate synaptic MAGUK protein interactions. , eLife 8 (2019), p. e41299/1-20
doi: 10.7554/eLife.41299
Schlesier, C.; Liu, F.; Dubrovin, V.; Spree, L.; Büchner, B.; Avdoshenko, S.M.; Popov, A.A.: Mixed dysprosium-lanthanide nitride clusterfullerenes DyM2N@C80-Ih and Dy2MN@C80-Ih (M = Gd, Er, Tm, and Lu): synthesis, molecular structure, and quantum motion of the endohedral nitrogen atom. , Nanoscale 11 (2019), p. 13139-13153
doi: 10.1039/c9nr03593a
Liu, F.; Spree, L.: Molecular spinning top: visualizing the dynamics of M3N@C-80 with variable temperature single crystal X-ray diffraction. , Chemical Communications 55 (2019), p. 13000-13003
doi: 10.1039/c9cc06363c
Fu, Y.; Zhang, K.; Dmitrieva, E.; Liu, F.; Ma, J.; Weigand, J.J.; Popov, A.; Berger, R.; Pisula, W.; Liu, J.; Feng, X.: NBN-embedded Polycyclic Aromatic Hydrocarbons Containing Pentagonal and Heptagonal Rings. , Organic Letters 21 (2019), p. 1354-1358
doi: 10.1021/acs.orglett.9b00057
Muziol, T.M.; Tereba, N.; Podgajny, R.; Kedziera, D.; Wrzeszcz, G.: Solvent-assisted structural conversion involving bimetallic complexes based on the tris(oxalato)ferrate(iii) unit with the green -> blue -> red crystal color sequence. , Dalton Transactions 48 (2019), p. 11536-11546
doi: 10.1039/c9dt02216c
Faelber, K.; Dietrich, L.; Noel, J.K.; Wollweber, F.; Pfitzner, A.K.; Muhleip, A.; Sanchez, R.; Kudryashev, M.; Chiaruttini, N.; Lilie, H.; Schlegel, J.; Rosenbaum, E.; Hessenberger, M.; Matthaeus, C.; Kunz, S.; von der Malsburg, A.; Noe, F.; Roux, A.; van der Laan, M.; Kuhlbrandt, W.; Daumke, O.: Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1. , Nature 571 (2019), p. 429-433
doi: 10.1038/s41586-019-1372-3
Palm, G.J.; Reisky, L.; Boettcher, D.; Mueller, H.; Michels, E.A. P.; Walczak, M.C.; Berndt, L.; Weiss, M.S.; Bornscheuer, U.T.; Weber, G.: Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate. , Nature Communications 10 (2019), p. 1717/1-10
doi: 10.1038/s41467-019-09326-3
Malecki, P.H.; Rueger, N.; Roatsch, M.; Krylova, O.; Link, A.; Jung, M.; Heinemann, U.; Weiss, M.S.: Structure-Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases. , ChemMedChem 14 (2019), p. 1828-1839
doi: 10.1002/cmdc.201900441
Driller, Jan: Studies on the assembly and architecture of the Drosophila active zone scaffold. , Berlin, Freie Universität Berlin, Diss., 2019
Petrick, Joy Kristin: Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery. , Uni Marburg, 2019
Krause, S.; Evans, J.D.; Bon, V.; Senkovska, I.; Iacomi, P.; Kolbe, F.; Ehrling, S.; Troschke, E.; Getzschmann, J.; Többens, D.; Franz, A.; Wallacher, D.; Yot, P.G.; Maurin, G.; Brunner, E.; Llewellyn, P.L.; Coudert, F.-X.; Kaskel, S.: Towards general network architecture design criteria for negative gas adsorption transitions in ultraporous frameworks. , Nature Communications 10 (2019), p. 3632/1-12
doi: 10.1038/s41467-019-11565-3
Janek, M.; Muziol, T.M.; Piszczek, P.: Trinuclear Oxo-Titanium Clusters: Synthesis, Structure, and Photocatalytic Activity. , Materials 12 (2019), p. 3195/1-17
doi: 10.3390/ma12193195
2018
Skerra, A.; Barkovskiy, M.; Ilyukhina, E.; Dauner, M.; Eichinger, A.: An engineered lipocalin that tightly complexes the plant poison colchicine for use as antidote as well as bioanalytical applications. , Biological Chemistry 400 (2018), p. 351-366
doi: 10.1515/hsz-2018-0342
Borchert, A.; Kalms, J.; Roth, S.; Rademacher, M.; Schmidt, A.; Holzhutter, H.; Kuhn, H.; Scheerer, P.: Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction. , Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1863 (2018), p. 1095-1107
doi: 10.1016/j.bbalip.2018.06.006
Pietrzyk-Brzezinska, A.J.; Absmeier, E.; Klauck, E.; Wen, Y.; Antelmann, H.; Wahl, M.C.: Crystal Structure of the Escherichia coli DExH-Box NTPase HrpB. , Structure 26 (2018), p. 1462-1473.e4
doi: 10.1016/j.str.2018.07.013
Kultaeva, A.; Bon, V.; Weiss, M.S.; Pöppl, A.; Kaskel, S.: Elucidating the Formation and Transformation Mechanisms of the Switchable Metal-Organic Framework ELM-11 by Powder and Single-Crystal EPR Study. , Inorganic Chemistry 57 (2018), p. 11920-11929
doi: 10.1021/acs.inorgchem.8b01241
Wiechert, Franziska: Heterologous expression of the antifungal protein AFP from Aspergillus giganteus in Escherichia Coli. , Berlin, Technische Universität, Bachelor, 2018
Mantoni, F.; Paiardini, A.; Brunotti, P.; D'Angelo, C.; Cervoni, L.; Paone, A.; Cappellacci, L.; Petrelli, R.; Ricciutelli, M.; Leoni, L.; Rampioni, G.; Arcovito, A.; Rinaldo, S.; Cutruzzolà, F.; Giardina, G.: Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonasaeruginosa. , FEBS Journal 285 (2018), p. 3815-3834
doi: 10.1111/febs.14634
Wollenhaupt, J.; Henning, L.M.; Sticht, J.; Becke, C.; Freund, C.; Santos, K.F.; Wahl, M.C.: Intrinsically Disordered Protein Ntr2 Modulates the Spliceosomal RNA Helicase Brr2. , Biophysical Journal 114 (2018), p. 788-799
doi: 10.1016/j.bpj.2017.12.033
Krylov, D.S.; Liu, F.; Brandenburg, A.; Spree, L.; Bon, V.; Kaskel, S.; Wolter, A.U.B.; Buechner, B.; Avdoshenko, S.M.; Popov, A.A.: Magnetization relaxation in the single-ion magnet DySc2N@C-80: quantum tunneling, magnetic dilution, and unconventional temperature dependence. , Physical Chemistry Chemical Physics 20 (2018), p. 11656-11672
doi: 10.1039/c8cp01608a
Qureshi, B.M.; Schmidt, A.; Behrmann, E.; Buerger, J.; Mielke, T.; Spahn, C.M.T.; Heck, M.; Scheerer, P.: Mechanistic insights into the role of prenyl-binding protein PrBP/delta in membrane dissociation of phosphodiesterase 6. , Nature Communications 9 (2018), p. 90/1-12
doi: 10.1038/s41467-017-02569-y
Czyrko, J.; Sliwiak, J.; Imiolczyk, B.; Gdaniec, Z.; Jaskolski, M.; Brzezinski, K.: Metal-cation regulation of enzyme dynamics is a key factor influencing the activity of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa. , Scientific Reports 8 (2018), p. 11334/1-15
doi: 10.1038/s41598-018-29535-y
Weber, G.; DeKoster, G.T.; Holton, N.; Hall, K.B.; Wahl, M.C.: Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. , Nature Communications 9 (2018), p. 2220
doi: 10.1038/s41467-018-04561-6
Knutsson, S.; Engdahl, C.; Kumari, R.; Forsgren, N.; Lindgren, C.; Kindahl, T.; Kitur, S.; Wachira, L.; Kamau, L.; Ekström, F.; Linusson, A.: Noncovalent Inhibitors of Mosquito Acetylcholinesterase 1 with Resistance-Breaking Potency. , Journal of Medicinal Chemistry 61 (2018), p. 10545-10557
doi: 10.1021/acs.jmedchem.8b01060
Hnizda, A.; Fabry, M.; Moriyama, T.; Pachl, P.; Kugler, M.; Brinsa, V.; Ascher, D.; Carroll, W.; Novak, P.; Zaliova, M.; Trka, J.; Rezacova, P.; Yang, J.; Veverka, V.: Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation. , Leukemia 32 (2018), p. 1393-1403
doi: 10.1038/s41375-018-0073-5
Scheib, U.; Broser, M.; Constantin, O.; Yang, S.; Gao, S.; Mukherjee, S.; Stehfest, K.; Nagel, G.; Gee, C.; Hegemann, P.: Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 angstrom structure of the adenylyl cyclase domain. , Nature Communications 9 (2018), p. 2046/1-15
doi: 10.1038/s41467-018-04428-w
Kock, M.; Brückner, S.; Wozniak, N.; Maestre-Reyna, M.; Veelders, M.; Schlereth, J.; Mösch, H.U.; Essen, L.O.: Structural and Functional Characterization of PA14/Flo5-Like Adhesins FromKomagataella pastoris. , Frontiers in Microbiology 9 (2018), p. 2581/1-17
doi: 10.3389/fmicb.2018.02581
Wilk, P.; Uehlein, M.; Piwowarczyk, R.; Dobbek, H.; Mueller, U.; Weiss, M.S.: Structural basis for prolidase deficiency disease mechanisms. , FEBS Journal 285 (2018), p. 3422-3441
doi: 10.1111/febs.14620
Schiefner, A.; Naestle, L.; Landgraf, M.; Reichert, A.J.; Skerra, A.: Structural Basis for the Specific Cotranslational Incorporation of p-Boronophenylalanine into Biosynthetic Proteins. , Biochemistry 57 (2018), p. 2597-2600
doi: 10.1021/acs.biochem.8b00171
Schmidt, A.; Sauthof, L.; Szczepek, M.; Fernandez Lopez, M.; Velazquez Escobar, F.; Qureshi, B.M.; Michael, N.; Buhrke, D.; Stevens, T.; Kwiatkowski, D.; von Stetten, D.; Mroginski, M.; Krauß, N.; Lamparter, T.; Hildebrandt, P.; Scheerer, P.: Structural snapshot of a bacterial phytochrome in its functional intermediate state. , Nature Communications 9 (2018), p. 4912/1-13
doi: 10.1038/s41467-018-07392-7
Antoshvili, M.; Caspy, I.; Hippler, M.; Nelson, N.: Structure and function of photosystem I in Cyanidioschyzon merolae. , Photosynthesis Research 139 (2018), p. 499-508
doi: 10.1007/s11120-018-0501-4
Franz, S.; Ignatz, E.; Wenzel, S.; Zielosko, H.; Putu, E.P.G.N.; Maestre-Reyna, M.; Tsai, M.D.; Yamamoto, J.; Mittag, M.; Essen, L.O.: Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii. , Nucleic Acids Research 46 (2018), p. 8010-8022
doi: 10.1093/nar/gky621
Janek, M.; Radtke, A.; Muziol, T.M.; Jerzykiewicz, M.; Piszczek, P.: Tetranuclear Oxo-Titanium Clusters with Different Carboxylate Aromatic Ligands: Optical Properties, DFT Calculations, and Photoactivity. , Materials 11 (2018), p. 1661/1-17
doi: 10.3390/ma11091661
Imber, M.; Vu Van Loi, ; Reznikov, S.; Fritsch, V.N.; Pietrzyk-Brzezinska, A.J.; Prehn, J.; Hamilton, C.; Wahl, M.C.; Bronowska, A.K.; Antelmann, H.: The aldehyde dehydrogenase AldA contributes to the hypochlorite defense and is redox-controlled by protein S-bacillithiolation in Staphylococcus aureus. , Redox Biology 15 (2018), p. 557-568
doi: 10.1016/j.redox.2018.02.001
Kobylarczyk, J.; Augustyniak, K.; Chorazy, S.; Nowicka, B.; Pinkowicz, D.; Kozie¿, M.; Muzio¿, T.; Podgajny, R.: The cyanido-bridged clusters with the remote N-oxide groups for branched multimetalic systems. , Crystal Growth & Design 18 (2018), p. 4766-4776
doi: 10.1021/acs.cgd.8b00860
Fiorillo, A.; Petrosino, M.; Ilari, A.; Pasquo, A.; Cipollone, A.; Maggi, M.; Chiaraluce, R.; Consalvi, V.: The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme. , PLoS One 13 (2018), p. e0199191/1-22
doi: 10.1371/journal.pone.0199191
Kalms, J.; Schmidt, A.; Frielingsdorf, S.; Utesch, T.; Gotthard, G.; von Stetten, D.; van der Linden, P.; Royant, A.; Mroginski, M.; Carpentier, P.; Lenz, O.; Scheerer, P.: Tracking the route of molecular oxygen in O-2-tolerant membrane-bound [NiFe] hydrogenase. , Proceedings of the National Academy of Sciences of the United States of America : PNAS 115 (2018), p. E2229-E2237
doi: 10.1073/pnas.1712267115
2017
Krause, S.; Bon, V.; Stoeck, U.; Senkovska, I.; Többens, D.; Wallacher, D.; Kaskel, S.: A Stimuli-Responsive Zirconium Metal-Organic Framework Based on Supermolecular Design. , Angewandte Chemie - International Edition 56 (2017), p. 10676-10680
doi: 10.1002/anie.201702357
Kiontke, S.; Langemeyer, L.; Kuhlee, A.; Schuback, S.; Raunser, S.; Ungermann, C.; Kümmel, D.: Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1-Ccz1. , Nature Communications 8 (2017), p. 14034/1-10
doi: 10.1038/ncomms14034
Jancarikova, G.; Houser, J.; Dobes, P.; Demo, G.; Hyrsl, P.; Wimmerova, M.: Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. , PLoS Pathogens 13 (2017), p. 1006564/1-28
doi: 10.1371/journal.ppat.1006564
Consentius, P.; Gohlke, U.; Loll, B.; Alings, C.; Heinemann, U.; Wahl, M.; Risse, T.: Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals. , Physical Chemistry Chemical Physics 19 (2017), p. 20723-20734
doi: 10.1039/c7cp03144k
Müller, P.; Bon, V.; Senkovska, I.; Getzschmann, J.; Weiss, M.S.; Kaskel, S.: Crystal Engineering of Phenylenebis(azanetriyl))tetrabenzoate Based Metal-Organic Frameworks for Gas Storage Applications. , Crystal Growth & Design 17 (2017), p. 3221-3228
doi: 10.1021/acs.cgd.7b00184
Zhang, F.; Ma, H.; Bowatte, K.; Kwiatkowski, D.; Mittmann, E.; Qasem, H.; Krauß, N.; Zeng, X.; Ren, Z.; Scheerer, P.; Yang, X.; Lamparter, T.: Crystal Structures of Bacterial (6-4) Photolyase Mutants with Impaired DNA Repair Activity. , Photochemistry and Photobiology 93 (2017), p. 323-330
doi: 10.1111/php.12699
Müller, Janis: Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A. , Uni Marburg, 2017
Speck, David: Expression and purification of bovine cone 3‘,5‘-cyclic nucleotide phosphodiesterase 6. , Berlin, Freie Universität Berlin, Master, 2017
Consentius, P.; Loll, B.; Gohlke, U.; Alings, C.; Müller, C.; Müller, R.; Teutloff, C.; Heinemann, U.; Kaupp, M.; Wahl, M.C.; Risse, T.: Internal Dynamics of the 3-Pyrroline-N-Oxide Ring in Spin-Labeled Proteins. , The Journal of Physical Chemistry Letters 8 (2017), p. 1113-1117
doi: 10.1021/acs.jpclett.6b02971
Klima, M.; Chalupska, D.; Rozycki, B.; Humpolickova, J.; Rezabkova, L.; Silhan, J.; Baumlova, A.; Dubankova, A.; Boura, E.: Kobuviral Non-structural 3A Proteins Act as Molecular Harnesses to Hijack the Host ACBD3 Protein. , Structure 25 (2017), p. 219-230
doi: 10.1016/j.str.2016.11.021
Weiss, M.S.: Long-Wavelength X-Ray Diffraction and Its Applications in Macromolecular Crystallography. , In: Alexander Wlodawer, Zbigniew Dauter, Mariusz Jaskolski [Ed.] : Protein crystallography : methods and protocolsNew York, NY: Humana Press, 2017 (Methods in Molecular Biology ; 1607). - ISBN 978-1-4939-6998-2, p. 401-420
doi: 10.1007/978-1-4939-7000-1_17
Mueller, P.; Wisser, F.M.; Freund, P.; Bon, V.; Senkovska, I.; Kaskel, S.: Optical Sensors Using Solvatochromic Metal Organic Frameworks. , Inorganic Chemistry 56 (2017), p. 14164-14169
doi: 10.1021/acs.inorgchem.7b02241
Glaenzer, J.; Peter, M.F.; Thomas, G.H.; Hagelueken, G.: PELDOR Spectroscopy Reveals Two Defined States of a Sialic Acid TRAP Transporter SBP in Solution. , Biophysical Journal 112 (2017), p. 109-120
doi: 10.1016/j.bpj.2016.12.010
Krylov, D.S.; Liu, F.; Avdoshenko, S.M.; Spree, L.; Weise, B.; Waske, A.; Wolter, A.U.B.; Büchner, B.; Popov, A.A.: Record-high thermal barrier of the relaxation of magnetization in the nitride clusterfullerene Dy2ScN@C80-Ih. , Chemical Communications 53 (2017), p. 7901-7904
doi: 10.1039/C7CC03580B
Chen, C-H.; Krylov, D.S.; Avdoshenko, S.M.; Liu, F.; Spree, L.; Yadav, R.; Alvertis, A.; Hozoi, L.; Nenkov, K.; Kostanyan, A.; Greber, T.; Wolter, A.U.B.; Popov, A.A.: Selective arc-discharge synthesis of Dy2S-clusterfullerenes and their isomer-dependent single molecule magnetism. , Chemical Science 8 (2017), p. 6451-6465
doi: 10.1039/C7SC02395B
Liu, F.; Krylov, D.S.; Spree, L.; Avdoshenko, S.M.; Samoylova, N.A.; Rosenkranz, M.; Kostanyan, A.; Greber, T.; Wolter, A.U.B.; Büchner, B.; Popov, A.A.: Single molecule magnet with an unpaired electron trapped between two lanthanide ions inside a fullerene. , Nature Communications 8 (2017), p. 16098/1-9
doi: 10.1038/ncomms16098
Ehrmann, F.R.; Stojko, J.; Metz, A.; Debaene, F.; Barandun, L.J.; Heine, A.; Diederich, F.; Cianferani, S.; Reuter, K.; Klebe, G.: Soaking suggests " alternative facts " : Only cocrystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-of-inhibition. , PLoS One 12 (2017), p. e0175723/1-30
doi: 10.1371/journal.pone.0175723
Balasubramaniyam Sivanandam, Arasu: Structural and Biochemical Analysis of GTPases of IMmunity-Associated Proteins (GIMAPs) and their Interaction Partners. , Berlin, Freie Universität Berlin, Diss., 2017
Metje, Janina: Structural characterization of autophagy related protein complexes. , Uni Göttingen, 2017
Kalms, Jacqueline: Structural examination of hydrophobic tunnels in proteins. , Berlin, Technische Universität, Diss., 2017
Barciszewski, Jakub: Strukturalne podstawy działania ludzkiej mięśniowej fosfatazy fruktozo-1,6-bisfosforanu = Structural basis of fructose-1,6-bisphosphatase function. , Poznan, Institute of Bioorganic Chemistry, Polish Academy of Sciences, thesis, 2017
Wilk, P.; Uehlein, M.; Kalms, J.; Dobbek, H.; Mueller, U.; Weiss, M.S.: Substrate specificity and reaction mechanism of human prolidase. , FEBS Journal 284 (2017), p. 2870-2885
doi: 10.1111/febs.14158
Kalms, J.; Banthiya, S.; Galemou Yoga, E.; Hamberg, M.; Holzhutter, H.-G.; Kuhn, H.; Scheerer, P.: The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. , Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1862 (2017), p. 463-473
doi: 10.1016/j.bbalip.2017.01.003
2016
Radeva, N.; Schiebel, J.; Wang, X.; Krimmer, S.G.; Fu, K.; Stieler, M.; Ehrmann, F.R.; Metz, A.; Rickmeyer, T.; Betz, M.; Winquist, J.; Park, A.Y.; Huschmann, F.U.; Weiss, M.S.; Mueller, U.; Heine, A.; Klebe, G.: Active Site Mapping of an Aspartic Protease by Multiple Fragment Crystal Structures: Versatile Warheads To Address a Catalytic Dyad. , Journal of Medicinal Chemistry 59 (2016), p. 9743-9759
doi: 10.1021/acs.jmedchem.6b01195
Rühmann, E.H.; Rupp, M.; Betz, M.; Heine, A.; Klebe, G.: Boosting Affinity by Correct Ligand Preorganization for the S2 Pocket of Thrombin: A Study by Isothermal Titration Calorimetry, Molecular Dynamics, and High-Resolution Crystal Structures. , ChemMedChem 11 (2016), p. 309-319
doi: 10.1002/cmdc.201500531
Yoga-Galemou, Etienne: Crystal structure analysis of the bacterial lipoxygenase from Pseudomonas aeruginosa. , Berlin, Freie Universität Berlin, Master, 2016
Abdullin, D.; Hagelueken, G.; Schiemann, O.: Determination of nitroxide spin label conformations via PELDOR and X-ray crystallography. , Physical Chemistry Chemical Physics 18 (2016), p. 10428-10437
doi: 10.1039/C6CP01307D
Graczer, E.; Szimler, T.; Garamszegi, A.; Konarev, P.V.; Labas, A.; Olah, J.; Pallo, A.; Svergun, D.I.; Merli, A.; Zavodszky, P.; Weiss, M.S.; Vast, M.: Dual Role of the Active Site Residues of Thermus thermophilus 3-Isopropylmalate Dehydrogenase: Chemical Catalysis and Domain Closure. , Biochemistry 55 (2016), p. 560-574
doi: 10.1021/acs.biochem.5b00839
Radeva, N.; Krimmer, S.G.; Stieler, M.; Fu, K.; Wang, X.; Ehrmann, F.R.; Metz, A.; Huschmann, F.U.; Weiss, M.S.; Mueller, U.; Schiebel, J.; Heine, A.; Klebe, G.: Experimental Active-Site Mapping by Fragments - Hot Spots Remote from the Catalytic Center of Endothiapepsin. , Journal of Medicinal Chemistry 59 (2016), p. 7561-7575
doi: 10.1021/acs.jmedchem.6b00645
Radeva, Nedyalka: From Active-Site Mapping to Lead Discovery using Fragment-based Approaches on the Aspartic protease Endothiapepsin. , Uni Marburg, 2016
Le Cong, Karoline-Luisa: Herstellung, Kristallisation und Strukturaufklärung von bovinem Rhodopsin im Komplex mit verschiedenen von G-Proteinen abgeleiteten Peptiden. , Berlin, Freie Universität Berlin, Bachelor, 2016
Schiebel, J.; Krimmer, S.G.; Röwer, K.; Knörlein, A.; Wang, X.; Park, A.Y.; Stieler, M.; Ehrmann, F.R.; Fu, K.; Radeva, N.; Krug, M.; Huschmann, F.U.; Glöckner, S.; Weiss, M.S.; Mueller, U.; Klebe, G.; Heine, A.: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. , Structure 24 (2016), p. 1398-1409
doi: 10.1016/j.str.2016.06.010
Albinana, C.B.; Machara, A.; Rezacova, P.; Pachl, P.; Konvalinka, J.; Kozisek, M.: Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza. , European Journal of Medicinal Chemistry 121 (2016), p. 100-109
doi: 10.1016/j.ejmech.2016.05.016
Hnizda, A.; Skerlova, J.; Fabry, M.; Pachl, P.; Sinalova, M.; Vrzal, L.; Man, P.; Novak, P.; Rezacova, P.; Veverka, V.: Oligomeric interface modulation causes misregulation of purine 5 '-nucleotidase in relapsed leukemia. , BMC Biology 14 (2016), p. 91
doi: 10.1186/s12915-016-0313-y
Zhang, Linlin: Proteases of Emerging Viruses as Targets for Broad-Spectrum Inhibitors. , Lübeck, Universität zu Lübeck, Diss., 2016
Koval, T.; Ostergaard, L.H.; Lehmbeck, J.; Norgaard, A.; Lipovova, P.; Duskova, J.; Skalova, T.; Trundova, M.; Kolenko, P.; Fejfarova, K.; Stransky, J.; Svecova, L.; Hasek, J.; Dohnalek, J.: Structural and Catalytic Properties of S1 Nuclease from Aspergillus oryzae Responsible for Substrate Recognition, Cleavage, Non-Specificity, and Inhibition. , PLoS One 11 (2016), p. e0168832/1-25
doi: 10.1371/journal.pone.0168832
Banthiya, S.; Kalms, J.; Yoga Galemou, E.; Ivanov, I.; Carpena, X.; Hamberg, M.; Kuhn, H.; Scheerer, P.: Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. , Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1861 (2016), p. 1681-1692
doi: 10.1016/j.bbalip.2016.08.002
Banerjee, A.; Herman, E.; Kottke, T.; Essen, L.O.: Structure of a Native-Like Aureochrome 1A Lov Domain Dimer from Phaeodactylum Tricornutum. , Structure 24 (2016), p. 171-178
doi: 10.1016/j.str.2015.10.022
Kundu, P.; Biswas, R.; Mukherjee, S.; Reinhard, L.; Dutta, A.; Mueller-Dieckmann, J.; Weiss, M.S.; Pal, N.K.; Das, A.K.: Structure-based Epitope Mapping of Mycobacterium tuberculosis Secretary Antigen MTC28. , Journal of Biological Chemistry 291 (2016), p. 13943-13954
doi: 10.1074/jbc.M116.726422
Ehrmann, Frederik Rainer: Strukturbasierte Entwicklung und Charakterisierung von Inhibitoren der TGT,ein mögliches Ziel zur Therapie der Bakterienruhr. , Uni Marburg, 2016
Horsten, Silke von: Strukturelle Basis signalinduzierter Änderungen in Phytochrom B sowie der Phytochrom-assoziierten Proteinphosphatase PAPP5. , Uni Marburg, 2016
Nagano, S.; Scheerer, P.; Zubow, K.; Michael, N.; Inomata, K.; Lamparter, T.; Krauss, N.: The Crystal Structures of the N-terminal Photosensory Core Module of Agrobacterium Phytochrome Agp1 as Parallel and Anti-parallel Dimers. , Journal of Biological Chemistry 291 (2016), p. 20674-20691
doi: 10.1074/jbc.M116.739136
Gerlach, M.; Müller, U.; Weiss, M.S.: The MX Beamlines BL14.1-3 at BESSY II. , Journal of Large Scale Research Facilities JLSRF 2 (2016), p. 2-47
doi: 10.17815/jlsrf-2-64
Müller, P.; Grünker, R.; Bon, V.; Pfeffermann, M.; Senkovska, I.; Weiss, M.S.; Feng, X.; Kaskel, S.: Topological control of 3,4-connected frameworks based on the Cu2-paddle-wheel node: tbo or pto, and why? , CrystEngComm 18 (2016), p. 8164-8171
doi: 10.1039/c6ce01513a
Consentius, P.; Gohlke, U.; Loll, B.; Alings, C.; Muller, R.; Heinemann, U.; Kaupp, M.; Wahl, M.; Risse, T.: Tracking Transient Conformational States of T4 Lysozyme at Room Temperature Combining X-ray Crystallography and Site-Directed Spin Labeling. , Journal of the American Chemical Society 138 (2016), p. 12868-12875
doi: 10.1021/jacs.6b05507
Oweis, W.; Padala, P.; Hassouna, F.; Cohen-Kfir, E.; Gibbs, D.R.; Todd, E.A.; Berndsen, C.E.; Wiener, R.: Trans-Binding Mechanism of Ubiquitin-like Protein Activation Revealed by a UBA5-UFM1 Complex. , Cell Reports 16 (2016), p. 3113-3120
doi: 10.1016/j.celrep.2016.08.067
Sparta, K.; Krug, M.; Heinemann, U.; Mueller, U.; Weiss, M.S.: XDSAPP 2.0. , Journal of Applied Crystallography 49 (2016), p. 1085-1092
doi: 10.1107/S1600576716004416
2015
Bowler, M.W.; Mueller, U.; Weiss, M.S.; Sanchez-Weatherby, J.; Sorensen, T.L.-M.; Thunnissen, M.M.G.M.; Ursby, T.; Gobbo, A.; Russi, S.; Bowler, M.G.; Brockhauser, S.; Svensson, O.; Cipriani, F.: Automation and Experience of Controlled Crystal Dehydration: Results from the European Synchrotron HC1 Collaboration. , Crystal Growth & Design 15 (2015), p. 1043-1054
doi: 10.1021/cg500890r
Monecke, T.; Dickmanns, A.; Weiss, M.S.; Port, S.A.; Kehlenbach, R.H.; Ficner, R.: Combining dehydration, construct optimization and improved data collection to solve the crystal structure of a CRM1-RanGTP-SPN1-Nup214 quaternary nuclear export complex. , Acta Crystallographica Section F - Structural Biology Communications 71 (2015), p. 1481-1487
doi: 10.1107/S2053230X15021524
Klingl, S.; Scherer, M.; Stamminger, T.; Muller, Y.A.: Controlled crystal dehydration triggers a space-group switch and shapes the tertiary structure of cytomegalovirus immediate-early 1 (IE1) protein. , Acta Crystallographica Section D - Biological Crystallography 71 (2015), p. 1493-1504
doi: 10.1107/S1399004715008792
Stevens, Tammo: Crystallographic Investigations on the Photosensory Core Module of Agrobacterium tumefaciens Phytochrome 2 (Agp2). , Berlin, Freie Universität Berlin, Bachelor, 2015
Ruehmann, E.; Betz, M.; Heine, A.; Klebe, G.: Fragment Binding Can Be Either More Enthalpy-Driven or Entropy-Driven: Crystal Structures and Residual Hydration Patterns Suggest Why. , Journal of Medicinal Chemistry 58 (2015), p. 6960-6971
doi: 10.1021/acs.jmedchem.5b00812
Oden, F.; Marino, S.; Brand, J.; Scheu, S.; Kriegel, C.; Olal, D.; Takvorian, A.; Westermann, J.; Yilmaz, B.; Hinz, M.; Daumke, O.; Höpken, U.; Müller, G.; Lipp, M.: Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma. , Molecular Oncology 9 (2015), p. 1348-1358
doi: 10.1016/j.molonc.2015.03.010
Port, Sarah A: Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-binding Sites Involved in Nucleocytoplasmic Transport. , Uni Göttingen, 2015
Lapkouski, M.; Hallberg, B.M.: Structure of mitochondrial poly(A) RNA polymerase reveals the structural basis for dimerization, ATP selectivity and the SPAX4 disease phenotype. , Nucleic Acids Research 43 (2015), p. 9065-9075
doi: 10.1093/nar/gkv861
Lardong, J.A.; Driller, J.H.; Depner, H.; Weise, C.; Petzoldt, A.; Wahl, M.C.; Sigrist, S.J.; Loll, B.: Structures of Drosophila melanogaster Rab2 and Rab3 bound to GMPPNP. , Acta Crystallographica Section F - Structural Biology Communications 71 (2015), p. 34-40
doi: 10.1107/S2053230X1402617X
Rühmann, Eggert Henning: Strukturelle und thermodynamische Charakterisierung der Fragment und Liganden Bindung an Thrombin. , Uni Marburg, 2015
Scheerer, P.; Zhang, F.; Kalms, J.; von Stetten, D.; Krauss, N.; Oberpichler, I.; Lamparter, T.: The Class III Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals a New Antenna Chromophore Binding Site and Alternative Photoreduction Pathways. , Journal of Biological Chemistry 290 (2015), p. 11504-11514
doi: 10.1074/jbc.M115.637868
Mueller, U.; Förster, R.; Hellmig, M.; Huschmann, F.U.; Kastner, A.; Malecki, P.; Pühringer, S.; Röwer, M.; Sparta, K.; Steffien, M.; Ühlein, M.; Wilk, P.; Weiss, M.S.: The macromolecular crystallography beamlines at BESSY II of the Helmholtz-Zentrum Berlin: Current status and perspectives. , The European Physical Journal Plus : EPJ Plus 130 (2015), p. 141/1-10
doi: 10.1140/epjp/i2015-15141-2
2014
Neeb, M.; Betz, M.; Heine, A.; Barandun, L.J.; Hohn, C.; Diederich, F.; Klebe, G.: Beyond Affinity: Enthalpy-Entropy Factorization Unravels Complexity of a Flat Structure-Activity Relationship for Inhibition of a tRNA-Modifying Enzyme. , Journal of Medicinal Chemistry 57 (2014), p. 5566-5578
doi: 10.1021/jm5006868
Hellmich, Julia: Cyanobacterial Photosystem II in a native-like superstructure at 2.44 Å resolution and first serial femtosecond X-ray studies. , Berlin, Technische Universität, Diss., 2014
Murina, V.N.; Melnik, B.S.; Filimonov, V.V.; Ühlein, M.; Weiss, M.S.; Müller, U.; Nikulin, A.D.: Effect of conserved intersubunit amino acid substitutions on Hfq protein structure and stability. , Biochemistry (Moscow) = Biokhimiya 79 (2014), p. 469-477
doi: 10.1134/S0006297914050113
Stoeck, Ulrich: Neue, poröse metallorganische Gerüstverbindungen und organometallische Koordinationspolymere : Darstellung, Charakterisierung und Evaluierung ihres Potentials für die Gasspeicherung und Katalyse. , Dresden, Technische Universität Dresden, Diss., 2014
Sakai, F.; Yang, G.; Weiss, M.S.; Liu, Y.; Chen, G.; Jiang, M.: Protein crystalline frameworks with controllable interpenetration directed by dual supramolecular interactions. , Nature Communications 5 (2014), p. 4634/1-8
doi: 10.1038/ncomms5634
Guettou, F.; Quistgaard, E.M.; Raba, M.; Moberg, P.; Low, C.; Nordlund, P.: Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. , Nature Structural & Molecular Biology 21 (2014), p. 728-731
doi: 10.1038/nsmb.2860
Klingl, Stefan: Structural analysis of the globular core domain of the immediate-early 1 protein of cytomegalovirus. , Erlangen, Nürnberg, Friedrich-Alexander-Universität Erlangen-Nürnberg, Diss., 2014
2013
Wandersleben, Traudy: Structural basis for dual regulation of spliceosomal helicase Brr2 by the Prp8 Jab1 domain and links to retinal disease. , Berlin, Freie Universität Berlin, Diss., 2013
Guettou, F.; Quistgaard, E.M.; Tresaugues, L.; Moberg, P.; Jegerschöld, C.; Zhu, L.; Jong, A.J.O.; Nordlund, P.; Löw, C.: Structural insights into substrate recognition in proton-dependent oligopeptide transporters. , EMBO Reports 14 (2013), p. 804-810
doi: 10.1038/embor.2013.107
2012
Mueller, U.; Darowski, N.; Fuchs, M.R.; Förster, R.; Hellmig, M.; Paithankar, K.S.; Pühringer, S.; Steffien, M.; Zocher, G.; Weiss, M.S.: Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin. , Journal of Synchrotron Radiation 19 (2012), p. 442-449
doi: 10.1107/S0909049512006395
Hoeppner, A.; Thomas, F.; Rueppel, A.; Hensel, R.; Blankenfeldt, W.; Bayer, P.; Faust, A.: Structure of the corrinoid: coenzyme M methyltransferase MtaA from Methanosarcina mazei. , Acta Crystallographica Section D - Biological Crystallography 68 (2012), p. 1549-1557
doi: 10.1107/S090744491203853X
Bulut, Haydar: Structures of carbohydrate, cysteine and cystine binding receptors of ATP-Binding Cassette (ABC) Transporters. , Berlin, Freie Universität Berlin, Diss., 2012
Krug, M.; Weiss, M.S.; Heinemann, U.; Mueller, U.: XDSAPP: a graphical user interface for the convenient processing of diffraction data using XDS. , Journal of Applied Crystallography 45 (2012), p. 568-572
doi: 10.1107/S0021889812011715
2011
Köster, H.; Craan, T.; Brass, S.; Herhaus, C.; Zentgraf, M.; Neumann, L.; Heine, A.; Klebe, G.: A Small Nonrule of 3 Compatible Fragment Library Provides High Hit Rate of Endothiapepsin Crystal Structures with Various Fragment Chemotypes. , Journal of Medicinal Chemistry 54 (2011), p. 7784-7796
doi: 10.1021/jm200642w
Licht, A.; Bulut, H.; Scheffel, F.; Daumke, O.; Wehmeier, U.F.; Saenger, W.; Schneider, E.; Vahedi-Faridi, A.: Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose. , Journal of Molecular Biology : jmb 406 (2011), p. 92-105
doi: 10.1016/j.jmb.2010.11.048
Knappe, D.; Zahn, M.; Sauer, U.; Schiffer, G.; Straeter, N.; Hoffmann, R.: Rational Design of Oncocin Derivatives with Superior Protease Stabilities and Antibacterial Activities Based on the High-Resolution Structure of the Oncocin-DnaK Complex. , ChemBioChem 12 (2011), p. 874-876
doi: 10.1002/cbic.201000792
Volkers, G.; Palm, G.J.; Weiss, M.S.; Wright, G.D.; Hinrichs, W.: Structural basis for a new tetracycline resistance mechanism relying on the TetX monooxygenase. , FEBS Letters 585 (2011), p. 1061 - 1066
doi: 10.1016/j.febslet.2011.03.012
2010
Küttner, E.B.; Kettner, K.; Keim, A.; Svergun, D.I.; Volke, D.; Singer, D.; Hoffmann, R.; Müller, E.-C.; Otto, A.; Kriegel, T.M.; Sträter, N.: Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis. , Journal of Biological Chemistry 285 (2010), p. 41019-41033
doi: 10.1074/jbc.M110.185850
Dauter, Z.; Jaskolski, M.; Wlodawer, A.: Impact of synchrotron radiation on macromolecular crystallography: a personal view. , Journal of Synchrotron Radiation 17 (2010), p. 433-444
doi: 10.1107/S0909049510011611
Faust, A.; Puehringer, S.; Darowski, N.; Panjikar, S.; Diederichs, K.; Mueller, U.; Weiss, M.S.: Update on the tutorial for learning and teaching macromolecular crystallography. , Journal of Applied Crystallography 43 (2010), p. 1230-1237
doi: 10.1107/S0021889810028189
MX 14.3